Douglas Robinson
Group Lead, Advanced Biostatistical Sciences EMD Serono
Seminars
Tuesday 21st July 2026
The Fit-for-Purpose Clinical Outcome-Driven Tiered Cutoff Strategy in ctDNA & Beyond
11:30 am
- Providing clarity on the necessary cutoff strategy for ctDNA, unsuring results are fit-for-purpose
- Apply tiered threshold strategies that balance sensitivity and specificity depending on clinical decision points and disease context
- Link biomarker cutoffs to meaningful clinical outcomes, strengthening regulatory confidence and enabling clearer clinical actionability
