Right Test, Right Setting: Balancing Cost, Feasibility & Fit-for-Purpose in Liquid Biopsies

  • How clinical use case, risk tolerance, and decision impact should dictate assay design, validation depth, and deployment setting across screening, MRD, and treatment monitoring
  • Practical trade-offs between analytical performance, cost, turnaround time, infrastructure, and scalability when moving liquid biopsy tools from trials into routine practice
  • Where AI can meaningfully enhance liquid biopsy workflows, and where added model complexity creates validation, regulatory, or adoption challenges without clear clinical gain